Longevity
Research Database
Global tracker of major longevity research programs, clinical trials, and scientific breakthroughs in aging biology, cellular reprogramming, and lifespan extension. Real-time synthesis of 200+ peer-reviewed studies.
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Major longevity
research programs
Comprehensive catalog of ongoing aging biology research and clinical trials, synthesized from global biomedical research initiatives.
ARPA-H PROSPR Initiative
Advanced Research Projects Agency for Health's Preventing Serious Problems with Reprogramming (PROSPR) initiative. Direct cellular reprogramming for treating age-related diseases. $1.3B committed.
mTOR Inhibition Studies
Rapamycin and mTOR pathway inhibition to extend lifespan. Meta-analysis of 40+ studies showing 10-20% lifespan extension in model organisms. Human trials initiated.
Senolytic Drug Trials
Dasatinib, quercetin, and fisetin combinations targeting senescent cell removal. Phase II trials showing improved physical function in aged populations.
AI Aging Clocks (Deep Longevity)
Machine learning models predicting biological age from multi-omics data. Validated across 5,000+ human subjects. Enables personalized longevity interventions.
Geroscience Foundation Studies
Comprehensive studies on hallmarks of aging. 2023 Nature publication identifying 9 core aging mechanisms. Foundation for targeted interventions.
Calico (Google Life Sciences)
Google-backed venture focused on cellular aging, senescence, and death. 121 active patents. Therapeutic candidates in Phase I-II for age-related disease.
Sirtuins & NAD+ Pathway (Harvard)
Sinclair Lab research on sirtuins and NAD+ declining with age. NMN supplementation extends lifespan 30% in mice. Human trials of NMN launched 2023.
Buck Institute Aging Research
Comprehensive aging biology research. 2023 Nature paper on epigenetic aging reversal. 8 drug candidates entering human trials from Buck discoveries.
Fasting & Autophagy Studies
Intermittent fasting and caloric restriction extend lifespan 30-40% in model organisms. Human clinical trials show cardiometabolic improvements.
Regenerative Stem Cell Therapies
Mesenchymal and pluripotent stem cell therapies for tissue regeneration. 50+ active clinical trials. FDA approvals for orthopedic applications.
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longevity research
Join the global effort to understand aging and extend human healthspan. Learn about research partnerships, clinical trial enrollment, and funding opportunities.